• CFD analyses of single and twin screw extruders were used to accurately predict decisive process parameters for various geometries.
• The geometry of a plate-type separator in the Kogenate^®  rFVIII process was improved markedly with regard to product quality.
• Local droplet size distribution for an organic phase in a continuous inorganic phase, and thus the mass transfer between both phases, was calculated to optimize the reaction progress in a tubular flow reactor.
• CFD was used together with rigorous modeling and data mining to optimize a fiber spinning process.
• The primary cause of fouling in a nozzle reactor was revealed through joint application of CFD and data mining.

Due to their high synergy potential custom-made joint applications will open up unique opportunities in engineering analysis.