Process Chromatography – economic, reliable, efficient
Competitiveness is not just a question of purity
Your production processes must be as efficient as possible if you hope to find success beyond your borders in the global marketplace. Today, competitiveness comes down to product quality and time to market. Especially when business is characterized by increasingly exacting customer requirements. The pharmaceutical, biopharmaceutical, fine chemicals, biotechnology, crop science and food & flavor sectors thus find themselves faced with new challenges. New and pioneering solutions are required, especially for specific separation problems. Chromatography, in particular, has proven to be a guarantee of quality and a valuable tool for difficult separation processes. In fact, chromatography is indispensable if high purity is required.
General Applications of Process Chromatography:
Synthetics
- Ion exchange
- Isomers
- Chiral
- Non-chiral (Reversed/Normal Phase)
Biologicals
- Ion exchange
- Size Exclusion
- Affinity
Holistic technological expertise
Bayer Technology Services has the expertise required for the entire life cycle of your support plants and processes. From development and planning through construction to the optimization of processes and plants. This interdisciplinary approach enables us to implement integrated solutions for you. You can rely on us to consider the problem from every angle. The result: enduring concepts that deliver in practice what the planning promised. By teaming with Merck, our preferred partner, we can also offer the development
of highly selective, high-performance adsorbents.
The full spectrum of chromatography – designed by Bayer Technology Services
Bayer Technology Services transposes chromatography processes to production scale. Thanks to the extensive international project management experience of our engineering
experts, you can be certain that your plant can be commissioned on time and within specification. We can even integrate the chromatography unit into production with minimized downtime.
We develop, plan and realize your custom batch or multicolumn unit. And it doesn’t end with commissioning; we will continue to support you to ensure trouble-free production.
Bayer Technology Services also offers additional services. We can recycle your solvents quickly and costeffectively, for example. We are also increasingly asked to produce test quantities within the framework of process development. We have the necessary apparatus and pilot plants to solve your separation tasks professionally and economically.
At a glance
Hardware:
- Chromatography units for batch or multi-column (SMB) operation
- HPLC, LPLC from lab to production scale
- Solvent storage, evaporation and buffer units
- Packing unit for dynamic axial compression, vacuum or slurry suspension
- Infrastructure e.g. energy supply, buildings
Services:
- Process development
- Minimization of total costs
- Optimal process integration
- Engineering, construction and commissioning
- Qualification, operation and validation support
- After-sales service
Technology Features:
Quick and easy operation increases product yield and production time via
- Patented process concept
- Unique control concept
- Online concentration monitoring for easy operation
- Fully automated process including cleaning and column testing
- Special valve technology
- Ideal fluid dynamics through optimized distribution plate
- Easy packing through special hydraulic concept and swivel plate







