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Bioprocess Engineering

Protein Crystallization Services

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Microscopic views of different protein crystal morphologies
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Mixture of different crystals of one protein

Our service ...

Process development in the novel and emerging field of protein crystallization for downstream processing is our core expertise.
The crystallization of proteins is a technique commonly used only for the determination of the three-dimensional structure of a protein. But in the crystalline state, proteins are usually more stable than dissolved and contain only low levels of impurities. Therefore, a number of possible applications for protein crystallization arise in an industrial downstream process. For example, the method might be beneficially used for purification, formulation or the stabilization of protein storage.

That is where our know-how and services come in. Starting with only a few milligrams of protein to find crystallization conditions, we are able to develop a technical process on a kilogram scale. Using our unique technology for protein crystallization scale-up, we are able to design a process with an optimized space-time yield.

We offer consultancy services for product design and also custom manufacturing services for protein crystallization.

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